SAIF
Sophisticated Analytical Instrument Facility

CSIR-Central Drug Research Institute, Lucknow

Supported by: Department of Science & Technology ( Govt. of India)

TRAINING

Topics to be covered: Overview of the Drug Discovery. Selection of raw material for Drug Discovery. Basics of HPLC /LC-MS and their applications. Applications of HPLC/LCMS for lead identification and dereplication of known bioactive agents. Biological assays, screening protocols, and services are available within the institute. Visit of CSIR-CDRI facility followed by discussion.

Topics to be covered: Basics of HPLC Basic Instrumentation of HPLC/PDA Applications of HPLC and their data interpretation. Demonstration on instrument (Lab. session) followed by discussion. Examination and result discussion.

Topics to be covered: Basics of Mass Spectrometry Basic Instrumentation of MS Applications of EI-MS, ESI-MS, APCI-MS, and their data interpretation. Demonstration on the instrument (Lab. session) followed by discussion. Exercise on mass spectrum data analysis. Examination and result discussion.

Topics to be covered Basics of Tandem Mass Spectrometry Basic Instrumentation of HPLC/LC-MS/MS Applications of ESI-MS/MS, LC-MS/MS, and their data interpretation. Demonstration on the instrument (Lab. session) followed by discussion. Exercise on mass spectrum data analysis. Examination and result discussion.

Topics to be covered: Basics of Chromatography and Mass Spectrometry Basic Instrumentation of HPLC/LC-MS Applications of ESI-MS, APCI-MS, LC-MS, and their data interpretation. Demonstration on the instrument (Lab. session) followed by discussion. Exercise on mass spectrum data analysis. Examination and result discussion.

Under CSIR-Integrated Skill Initiative, CSIR-Central Drug Research Institute is offering a course on SKILL DEVELOPMENT PROGRAM in Advanced Spectroscopic Techniques. It is intended to generate human resources with knowledge of operation, routine maintenance and interpretation of spectral data using state-of-the-art spectrometers to fulfil the need by enhancing the knowledge and skill-set of students, research fellows, faculty and staff working in the relevant area. During this training, exposure will be given to the state-of-the-art instruments i.e. NMR, Mass, HPLC, FT-IR, UV-Vis. This training program will provide knowledge about theoretical, practical training on basic and advanced experimental methods in these techniques. Also providing understanding and hands on experience on elucidating the structural information of various molecules in the field of drug discovery process.